The DeSoto (also spelled "Desoto") is Sam's beloved car in the Sam and Max universe. Specifically, it is a "DeSoto Adventurer", a limited number model of car from the 1950s-1960s.
With its black and white paint job and "Sam & Max: Freelance Police" decals on the side doors, it takes the duo where ever they need to go. It is capable of time-travel, driving underwater, taking its passengers into outer space, and extremely long car trips. In the animated series, it is equipped with a "Rat-Gat" ("it came free with our last muffler job") and was worked on by the Geek. In Telltale's Season 2, Sam and Max were able to collect back trunk decals and the C.O.P.S. gave them various upgrades.
It is referred as a "she" and has a soul which Sam and Max had to rescue from Hell. Returning from Hell did have a negative impact on the DeSoto as it now drives itself and tries to run over anything that moves. Sam let Abe and Sybil drive away in the possessed DeSoto after their wedding, but then was left wondering if that was such a good idea.
The DeSoto's license plate is RLW 822 (registered New York) in all versions except in the animated series which is SRP 695.