Brady Culture is the villain in the 1st episode of the 1st season: Culture Shock.
The Freelance Police catch wind of this scheme when the Soda Poppers visit their neighborhood and (amongst other things) try to forcibly put the Eye-Bo video's in Bosco's store. After de-hypnotizing all three, they go on to confront and eventually defeat Brady Culture. Max keeps his hair as a souvenir.
Reports on what happened to Brady afterwards are conflicting, with a newspaper suggesting he went to jail but the Soda Poppers saying they beat him to death. Sam & Max meet him again in hell in What's new, Beelzebub?, so it is at least clear that he died by then. His hypno-goggles can be seen in his cubicle, where he seems to be very happy working in hell.
He is also the only antagonist in season 1 that had almost nothing to do with Hugh Bliss.
- It is suggested that he had Incestual feeling towards his own mother due to his sign up admission says that a symptom of having Artificial Personality Disorder is to have a "unconscious desire to marry one's mother"